A neonatal hypertriglyceridemia presenting with respiratory distress: a rare case report

Sumit Bhatia, Payas Joshi, Jay Kishore, Chetnanand Jha


Neonatal hypertriglyceridemia is a very rare condition. Diagnosis in neonatal period is very difficult and is usually diagnosed when acute pancreatitis sets in. Early diagnosis is important as it can prevent the complications associated with the condition that is acute pancreatitis and pancreatic necrosis. Here we present a case of neonatal hypertriglyceridemia who presented to us with respiratory distress but was diagnosed early due to the presence of highly viscous and milky blood. This holds importance as early treatment can reduce the complications and morbidity associated with familial hypertriglyceridemia.



Hypertriglyceridemia, Milky blood, Neonatal

Full Text:



Boman H, Hazzard WR, Albers JJ, Cooper MN, Motulsky AG. Frequency of monogenic forms of hyperlipidemia in a normal population. Am J Hum Genet 1975;27(6):A19.

Hegele RA, Ginsberg HN, Chapman MJ, Nordestgaard BG, Kuivenhoven JA, Averna M, et al. The polygenic nature of hypertriglyceridemia: implications for definition, diagnosis, and management. Lancet Diabetes Endocrinol. 2014;2:655-66.

Pejic RN, Lee DT. Hypertriglyceridemia. JABFM. 2006;19:310-6.

Fredrickson DS, Lees RS. A system for phenotyping hypolipoproteinemia. Circ. 1965;31:321-7.

Kliegman R, Stanton B, Geme JW, Schor NF, Behrman RE. Nelson textbook of pediatrics. 20th Edition. Philadelphia, PA: Elsevier; 2016.

Brunzell JD, Miller NE, Alaupovic P. Familial chylomicronemia due to a circulating inhibitor of lipoprotein lipase activity. J Lipid Res. 1983;24(1):12-9.

Foil-Fonseca JC, Levy E, Godard M, Lambert M. Familial lipoprotein lipase deficiency in infancy: clinical, biochemical, and molecular study. J Pediatr. 1998;133(3):417-23.

Yuan G, Al-Shali KJ, Hegele RA Hypertriglyceridemia: its etiology, effects and treatment. Can Med Assoc J. 2007;176(8):1113-20.

Labossiere R, Goldberg IJ. Management of hypertriglyceridemia. Therapeutic Lipidol. Totowa: Humana Press; 2008:201-20.

Brunzell JD, Bierman EL. Chylomicronemia syndrome. Med Clin North Am. 1982;66:455-63.