Study of eosinophil count in nasal smear and peripheral blood smear in children with allergic rhinitis

Authors

  • Sudha Rudrappa Department of Paediatrics, Mysore Medical College and Research Institute, Mysore, Karnataka, India
  • Rajendra Kumar Department of Paediatrics, Mysore Medical College and Research Institute, Mysore, Karnataka, India
  • Vinay Kumar Department of Paediatrics, Mysore Medical College and Research Institute, Mysore, Karnataka, India

DOI:

https://doi.org/10.18203/2349-3291.ijcp20192004

Keywords:

Allergic respiratory disorders, Allergic rhinitis, Blood eosinophilia, Eosinophil, Gender distribution

Abstract

Background: Allergic respiratory disorders are the common cases seen in Pediatrics OPD. With an appropriate history and detailed examination, the diagnosis usually may not be problematic and routine investigations may not contribute much for the final diagnosis but may help in ruling other possibilities. The objectives of this study were done to know the eosinophil counts in nasal and blood smear and to assess the feasibility of nasal cytogram which is simple, economical and reliable investigation in patients of allergic respiratory disorders.

Methods: A prospective clinical correlation study conducted in outpatient visiting Mysore Medical College and Research Institute, Cheluvamba hospital Department of Pediatrics and ENT Department KR hospital. 60 children of age group between 2 to 18 years were selected to estimate the eosinophil count in nasal and peripheral smear in allergic rhinitis. All allergic rhinitis cases based on clinical signs and symptoms were selected and investigated for nasal and blood eosinophilia. The nasal and blood eosinophilia were compared with each other and the clinical findings of allergic rhinitis were studied.

Results: In this study peak age incidence is between 6-10 years and there is equal gender distribution. Seasonal variation and pollen allergens were the most common risk factors for allergic rhinitis. Running nose and the nasal obstruction were the most common symptoms in children with allergic rhinitis followed by sneezing and itching. One tenth of the children with allergic rhinitis had bronchial asthma. Nasal eosinophilia contributes to the diagnosis of allergic rhinitis as compared blood eosinophilia. Mild intermittent variety of allergic rhinitis was the most common form of allergic rhinitis.

Conclusions: Among various risk factors for allergic rhinitis, seasonal variation and pollen allergens have significant association with the severity of allergic rhinitis. Among various symptomology, only itching had a significant relation to the severity of allergic rhinitis.

References

Cummings CW, Fredricson JM, Harker LA, Krauss CJ, Mark A, eds. Richardson. In: allergic rhinitis. otolaryngology head and neck surgery. 3rd Ed. Volume 2; 904-5.

International consensus reports on diagnosis and management of rhinitis. International rhinitis management working group. Allergy. 1994;49 (19):1-34.

Akbari H, Farid-Hosseini R, Miri S, Amin R. The prevalence of allergic rhinitis among 11-15 years-old children in Shiraz. Iran J Immunol. 2004;1(2):133-7.

Miller RE, Paradise JL, Friday GA, Fireman P, Voith D. The nasal smear for eosinophils: Its value in children with seasonal allergic rhinitis. Am J Dis Children. 1982;136(11):1009-11.

Arshad SH, Matthews S, Gant C, Hide DW. Prevention of atopic disease in children. Lancet. 1992;339:1493-7.

Venkateswarlu V, Mohan M KV. A comparative study of nasal smear eosinophilia v/s absolute eosinophilic count in patients with allergic rhinitis. MRIMS J Health Sci. 2015; 3(1):36-8.

Pokharel PK, Pokharel P, Bhatia NK, Pandey RM, Erkki K. Asthma symptomatic school children of Sonapur. Kathamandu Univ Med J. 2007;5(4):484-7.

Kumar N, Bylappa K, Ramesh AC, Swetha R. A study of eosinophis count in the nasal and blood smear in allergic respiratory diseases in a rural set up. Internet J Med update. 2012; 7(1):40-6.

Ghazi BM, Imamzadehgan R, Aghamohammadi A, Darakhshavari R, Rezaei N. Frequency of allergic rhinitis in school-age children (7-18 years) in Tehran. Iranian J allergy asthma Immunol. 2003;2(4):181-4.

Shetty SS, Rai S, Somayaji GKS, Ali. Nasal smear eosinophil count vs AEC of patients diagnosed with allergic rhinitis attending a tertiary care hospital and the effect of treatment with a topical steroid nasal spray. J Dental Med Sci. 2014;13(1):7-2.

Crobach M, Hermans J, Kaptein A, Ridderikhoff J, Mulder J. Nasal smear eosinophilia for the diagnosis of allergic rhinitis and eosinophilic non-allergic rhinitis. Scandinavian J Primary Health Care. 1996;14(2):116-21.

Chowdary VS, Vinaykumar EC, Rao JJ, Rao R, Babu KR, Rangamani V. A study on serum IgE and eosinophils in respiratory allergy patients. Indian J allergy asthma Immunol. 2003;17(1):21-4.

Sanli A, Aydin S, Ateş G, Eken M, Celebi O. Comparison of nasal smear eosinophilia with skin prick test positivity in patients with allergic rhinitis. Ear Nose Throat Specialized J. 2006;16(2):60-3.

Downloads

Published

2019-04-30

Issue

Section

Original Research Articles